Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798884 | 0.92 | PARP14 (0.37) | NOTUMPARP14MAPTLMNAMAPK1 | |
| SCHEMBL5796106 | 0.90 | P2RX3 (0.43) | NOTUMPARP14NPC1 | |
| SCHEMBL5799054 | 0.89 | FLT3 (0.38) | KIF11FTOFLT3PARP14ALDH1A1 | |
| SCHEMBL5798774 | 0.86 | PARP14 (0.43) | KIF11FTOFLT3PARP14ALDH1A1 | |
| SCHEMBL5798821 | 0.85 | MAPT (0.43) | KIF11FTOFLT3PARP14ALDH1A1 | |
| SCHEMBL5798816 | 0.85 | MAPT (0.43) | KIF11FTOFLT3PARP14ALDH1A1 | |
| SCHEMBL5796627 | 0.83 | KIF11 (0.46) | KIF11FTOFLT3PARP14ALDH1A1 | |
| SCHEMBL5799313 | 0.82 | KMT2A (0.38) | PARP14ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL5795508 | 0.82 | KIF11 (0.44) | KIF11FTOFLT3PARP14ALDH1A1 | |
| SCHEMBL5795513 | 0.81 | P2RX3 (0.42) | PARP14NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |