Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797097 | 0.90 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5796789 | 0.85 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5797343 | 0.83 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5799593 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5808893 | 0.81 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5799050 | 0.80 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL5799076 | 0.79 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5796608 | 0.79 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5796617 | 0.79 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2POLBBLM | |
| SCHEMBL5813364 | 0.77 | ALPL (0.46) | NPC1RAB9ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |