Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797667 | 0.85 | MAPT (0.54) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL5797343 | 0.84 | MAPT (0.50) | MAPTALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL5796789 | 0.84 | MAPT (0.58) | MAPTALDH1A1HSD17B10RAB9AKMT2A | |
| SCHEMBL5808893 | 0.82 | MAPT (0.48) | MAPTALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL5431174 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL5820244 | 0.80 | MAPT (0.49) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL5795596 | 0.80 | NPC1 (0.48) | MAPTALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL5799076 | 0.80 | RAB9A (0.57) | MAPTRAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5796821 | 0.78 | FAAH (0.44) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL28615347 | 0.76 | KMT2A (0.67) | MAPTALDH1A1HTTHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |