Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 15/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678778 | 0.71 | FFAR3 (0.35) | — | |
| SCHEMBL31053541 | 0.66 | DGAT1 (0.54) | HDAC4 | |
| SCHEMBL2558124 | 0.65 | FFAR3 (0.36) | — | |
| SCHEMBL5325135 | 0.63 | GRM2 (0.33) | — | |
| SCHEMBL13446458 | 0.62 | FFAR3 (0.38) | — | |
| SCHEMBL13223471 | 0.62 | GAA (0.33) | — | |
| SCHEMBL28001680 | 0.61 | — | — | |
| SCHEMBL3107018 | 0.60 | HDAC4 (0.42) | HDAC4 | |
| Hydrochloric Acid SCHEMBL11798891 | 0.60 | HDAC4 (0.39) | HDAC4 | |
| SCHEMBL1464652 | 0.60 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678166-A2 | PROTEIN KINASE INHIBITORS | Arizona Board of Regents on behalf of The University of Arizona (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005037825-A2 | PROTEIN KINASE INHIBITORS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2005-04-28 | — | — | WO | disclosed |