SCHEMBL1464652

SCHEMBL1464652

CC(C)(C)C1(C(N)=O)CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 2/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 2/20 0.31
USP2 O75604 1/20 0.31
CYP1A2 P05177 1/20 0.31
BLM P54132 1/20 0.31
CACNA2D1 P54289 1/20 0.31
CYP2C19 P33261 1/20 0.31
PKM P14618 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13223471 0.97 GAA (0.33) ALDH1A1SMN1; SMN2LMNAGAAPKM
SCHEMBL1090915 0.92 GAA (0.33) GAAPKMKDM4EKMT2A
SCHEMBL1091554 0.87 KDM4E (0.38) LMNAGAABLMPKMKDM4E
SCHEMBL14136846 0.86 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2LMNA
SCHEMBL11376972 0.86 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2LMNA
SCHEMBL14136780 0.83 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2PKM
SCHEMBL28038472 0.82 CYP2C19 (0.30) CYP2C19
SCHEMBL22958 0.80 CYP2C19 (0.38) ALDH1A1SMN1; SMN2LMNATSHRUSP2
SCHEMBL14825438 0.80 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2
SCHEMBL14136865 0.78 PKM (0.30) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903448-A1 HARD CONFECTIONARY AND METHOD OF MANUFACTURE THEREOF Intercontinental Great Brands LLC (US) 2015-08-12 EP claimed
CN-104684406-A Hard confectionery and method of making same INTERCONTINENTAL GREAT BRANDS LLC 2015-06-03 CN claimed
EP-4630407-A1 2-METHYL-2-(1-METHYLCYCLOHEXYL)PROPANAMIDE DERIVATIVES AND 1-(TERT-BUTYL)-CYCLOHEXANE-1-CARBOXAMIDE DERIVATIVES FOR USE IN UMAMI FLAVOR COMPOSITIONS International Flavors & Fragrances, Inc. (US) 2025-10-15 EP disclosed
EP-4630407-A1 2-METHYL-2-(1-METHYLCYCLOHEXYL)PROPANAMIDE DERIVATIVES AND 1-(TERT-BUTYL)-CYCLOHEXANE-1-CARBOXAMIDE DERIVATIVES FOR USE IN UMAMI FLAVOR COMPOSITIONS International Flavors & Fragrances, Inc. (US) 2025-10-15 EP disclosed
EP-4630407-A1 2-METHYL-2-(1-METHYLCYCLOHEXYL)PROPANAMIDE DERIVATIVES AND 1-(TERT-BUTYL)-CYCLOHEXANE-1-CARBOXAMIDE DERIVATIVES FOR USE IN UMAMI FLAVOR COMPOSITIONS International Flavors & Fragrances, Inc. (US) 2025-10-15 EP disclosed
CN-120435456-A 2-Methyl-2- (1-methylcyclohexyl) propanamide derivatives and 1- (tert-butyl) -cyclohexane-1-carboxamide derivatives for umami flavour compositions 国际香料和香精公司 2025-08-05 CN disclosed
CN-120435456-A 2-Methyl-2- (1-methylcyclohexyl) propanamide derivatives and 1- (tert-butyl) -cyclohexane-1-carboxamide derivatives for umami flavour compositions 国际香料和香精公司 2025-08-05 CN disclosed
WO-2024123607-A1 2-METHYL-2-(1-METHYLCYCLOHEXYL)PROPANAMIDE DERIVATIVES AND 1-(TERT-BUTYL)-CYCLOHEXANE-1-CARBOXAMIDE DERIVATIVES FOR USE IN UMAMI FLAVOR COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2024-06-13 WO disclosed
EP-2903448-B1 HARD CONFECTIONARY AND METHOD OF MANUFACTURE THEREOF INTERCONTINENTAL GREAT BRANDS LLC (US) 2021-08-18 EP disclosed
WO-2017105634-A1 CHEWING GUM COMPOSITIONS HAVING CONTROLLED RELEASE OF COOLING AGENTS AND METHODS OF MANUFACTURE INTERCONTINENTAL GREAT BRANDS LLC (US) 2017-06-22 WO disclosed
US-9504266-B2 Photodegradable gum base, a chewing gum comprising the photodegradable gum base and methods of making the same INTERCONTINENTAL GREAT BRANDS LLC (US) 2016-11-29 US disclosed
US-20100204119-A1 4-AMINO-5-OXO-7,8-DIHYDROPYRIMIDO[5,4-F][1,4]OXAZEPIN-6(5H)-YL PHENYL DERIVATIVES PFIZER INC 2010-08-12 US disclosed
US-20050043411-A1 Process for preparing homophthalate derivatives TJGEL, LLC 2005-02-24 US disclosed
US-6797838-B2 Process for preparing homophthalate derivatives ILEX PRODUCTS, INC. 2004-09-28 US disclosed
EP-1404662-A2 PROCESS FOR PREPARING ISOCOUMARINS Ilex Products, Inc. (US) 2004-04-07 EP disclosed
US-20040024240-A1 Process for preparing homophthalate derivatives GENZYME CORPORATION 2004-02-05 US disclosed
US-6664401-B2 Reacting a isochroman-1,3-dione with a carbonyl compound whose carbonyl group is substituted with an acyl activating group, in the presence of a base and a solvent; use making anticancer agents for example ILEX PRODUCTS, INC. 2003-12-16 US disclosed
US-20030105340-A1 Process for preparing isocoumarins GENZYME CORPORATION 2003-06-05 US disclosed
WO-2003004486-A2 PROCESS FOR PREPARING ISOCOUMARINS ILEX PRODUCTS, INC. (US) 2003-01-16 WO disclosed
US-4283420-A ANTICONVULSANTS, ANTIANAPHYLACTIC AGENTS, ANTIPSYCHOTIC AGENTS LABAZ (FR) 1981-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204119-A1 4-AMINO-5-OXO-7,8-DIHYDROPYRIMIDO[5,4-F][1,4]OXAZEPIN-6(5H)-YL PHENYL DERIVATIVES DGAT1, DGAT2, MOGAT2 ALDH1A1 158/4885SMN1; SMN2 2977/4885LMNA 4019/4885
US-20030105340-A1 Process for preparing isocoumarins DHPS, IDH2, IDH1 ALDH1A1 1178/4885SMN1; SMN2 4741/4885LMNA 2099/4885
US-20050043411-A1 Process for preparing homophthalate derivatives HPD, HAAO, PAH ALDH1A1 669/4885SMN1; SMN2 4831/4885LMNA 1932/4885
US-20040024240-A1 Process for preparing homophthalate derivatives HPD, HAAO, PAH ALDH1A1 669/4885SMN1; SMN2 4831/4885LMNA 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.