Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 10/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811399 | 0.66 | CNR1 (0.65) | RPA1UGCGCNR1CNR2 | |
| SCHEMBL5811121 | 0.66 | UGCG (0.46) | UGCGCNR1CNR2 | |
| SCHEMBL25416376 | 0.65 | PDE4D (0.50) | UGCGMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11018665 | 0.65 | L3MBTL1 (0.53) | RPA1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5806767 | 0.63 | RPA1 (0.44) | RPA1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL1432360 | 0.63 | CNR1 (0.43) | RPA1UGCGCNR1CNR2 | |
| SCHEMBL9183007 | 0.62 | MAPK1 (0.68) | RPA1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2201331 | 0.61 | LMNA (0.60) | RPA1MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL10772842 | 0.60 | PKM (0.43) | RPA1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL9178737 | 0.59 | CNR1 (0.47) | RPA1ALDH1A1L3MBTL1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030124-A1 | CONDENSED PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2006-03-23 | — | — | WO | disclosed |