Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15652568 | 0.89 | NR1H4 (0.60) | MAPTKDM4EHTTKMT2ATP53 | |
| SCHEMBL5789931 | 0.87 | MAPT (0.74) | MAPTKDM4EHTTKMT2ATP53 | |
| SCHEMBL5757229 | 0.82 | MAPT (0.65) | MAPTKDM4EHTTKMT2ATP53 | |
| SCHEMBL3755964 | 0.81 | MAPT (0.78) | MAPTKDM4EHTTKMT2ATP53 | |
| SCHEMBL6504855 | 0.80 | PPARD (0.65) | HDAC1HDAC6 | |
| SCHEMBL8011597 | 0.79 | MLYCD (0.77) | MAPTKDM4EHTTKMT2AHPGD | |
| SCHEMBL12764349 | 0.78 | MAPT (0.65) | MAPTKDM4EHTTKMT2ATP53 | |
| SCHEMBL1547783 | 0.77 | KMT2A (0.53) | KMT2APOLBALDH1A1HPGDHDAC1 | |
| SCHEMBL6670831 | 0.77 | ALDH1A1 (0.56) | MAPTKDM4EHTTKMT2AMAPK1 | |
| SCHEMBL29951436 | 0.77 | ALDH1A1 (0.56) | MAPTKDM4EHTTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006041921-A2 | PREPARATION AND USES OF RHODANINE DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |