Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5796209

CC1=CC2Oc3cc2ccc31.N

nearest known ligand 0.35

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.35
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4603082 0.47
SCHEMBL16369469 0.47 CYP19A1 (0.46) MAOBNPC1
SCHEMBL19807395 0.47
Hydrochloric Acid SCHEMBL8149159 0.45 POLB (0.45)
SCHEMBL1120426 0.45 TSHR (0.56) MAOB
Ammonia Solution, Strong SCHEMBL4602569 0.44
SCHEMBL18919018 0.43 ACHE (0.47)
SCHEMBL1134729 0.42 MAOA (0.55) MAOB
SCHEMBL1134706 0.42 MAOA (0.55) MAOB
SCHEMBL31103 0.41

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025683-A1 ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2006-03-09 WO disclosed