Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207957 | 0.88 | MAPT (0.66) | MAPTDRD4ALDH1A1TSHRMEN1 | |
| SCHEMBL3056156 | 0.87 | HTR1A (0.68) | MAPTDRD4ALDH1A1TSHRMEN1 | |
| SCHEMBL3057035 | 0.85 | DRD2 (0.59) | DRD4ALDH1A1KDM4ETDP1DRD2 | |
| SCHEMBL4171472 | 0.85 | KDM4E (0.65) | MAPTDRD4ALDH1A1TSHRMEN1 | |
| SCHEMBL8443672 | 0.85 | ALDH1A1 (0.65) | MAPTDRD4ALDH1A1TSHRMEN1 | |
| SCHEMBL5796448 | 0.83 | KDM4E (0.70) | MAPTDRD4ALDH1A1TSHRMEN1 | |
| SCHEMBL4171468 | 0.82 | ALDH1A1 (0.65) | MAPTDRD4ALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL1375643 | 0.82 | ALDH1A1 (0.69) | MAPTDRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3068737 | 0.81 | DRD3 (0.54) | DRD4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5821193 | 0.81 | DRD4 (0.61) | MAPTDRD4ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006018815-A1 | PIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-23 | — | — | WO | disclosed |