Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.95 |
| ▸ | MTOR | P42345 | 1/20 | 0.95 |
| ▸ | ADK | P55263 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148367 | 0.98 | NISCH (0.91) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL8901 | 0.98 | NISCH (1.00) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL9719773 | 0.98 | NISCH (1.00) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL1954238 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL1881537 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL31511436 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL11072040 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL5796856 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL8898735 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL28193283 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674879-A | Compositions including and methods of using conformationally restricted angiotensin II antagonist | G.D. SEARLE & CO. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5426105-A | Cardiovascular disorders | G.D. SEARLE & CO. (US) | 1995-06-20 | — | — | US | disclosed |