Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799782 | 0.91 | MAPT (0.59) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL5807692 | 0.89 | KMT2A (0.55) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL5795590 | 0.85 | TOP2A (0.58) | KMT2AMAPTMEN1DYRK1ASMN1; SMN2 | |
| SCHEMBL5796715 | 0.80 | MAPT (0.46) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL5799660 | 0.77 | TOP2A (0.58) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL5797428 | 0.76 | SCD (0.58) | KMT2AMAPTMEN1DYRK1ASMN1; SMN2 | |
| SCHEMBL5005629 | 0.72 | RIPK1 (0.72) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL3749121 | 0.72 | RIPK1 (0.68) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL16747337 | 0.72 | DYRK1A (0.77) | KMT2AMAPTMEN1DYRK1APOLB | |
| SCHEMBL3924050 | 0.72 | DYRK1A (1.00) | KMT2AMAPTMEN1DYRK1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |