Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808920 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5795578 | 0.88 | HDAC1 (0.66) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5796774 | 0.83 | MAPT (0.48) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5795757 | 0.82 | POLB (0.49) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5797374 | 0.82 | HDAC6 (0.59) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5799597 | 0.81 | NPC1 (0.50) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5795676 | 0.80 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5812423 | 0.78 | FFAR1 (0.56) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL5796204 | 0.78 | HDAC6 (0.83) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5796202 | 0.78 | HDAC6 (0.83) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |