Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456852 | 0.82 | KMT2A (0.58) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL102342 | 0.81 | RIPK1 (0.61) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL30259906 | 0.78 | RIPK1 (0.62) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL2905172 | 0.78 | KMT2A (0.77) | KMT2ARIPK1ALDH1A1LMNAMAPT | |
| SCHEMBL2904265 | 0.78 | ANPEP (0.61) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL2905338 | 0.78 | RIPK1 (0.62) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL31426228 | 0.78 | RIPK1 (0.58) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL29639573 | 0.78 | RIPK1 (0.58) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL28710986 | 0.78 | KMT2A (0.62) | KMT2ARIPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL11589808 | 0.77 | NPC1 (0.72) | KMT2ANPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |