Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664850 | 0.87 | KCNA5 (0.52) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1329466 | 0.83 | RIPK1 (0.60) | RIPK1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL12851863 | 0.83 | TAAR1 (0.56) | RIPK1KMT2ANPC1RAB9A | |
| SCHEMBL102342 | 0.81 | RIPK1 (0.61) | RIPK1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL24242025 | 0.81 | P2RX7 (0.54) | RIPK1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL2749015 | 0.80 | RIPK1 (0.52) | RIPK1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL28333273 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3416627 | 0.80 | RIPK1 (0.52) | RIPK1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2456852 | 0.79 | KMT2A (0.58) | RIPK1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL8583106 | 0.79 | LMNA (0.55) | RIPK1KMT2AKCNA5LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609905-B1 | PEPTIDE MACROCYCLES AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2022-06-08 | — | — | EP | disclosed |