Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797355 | 1.00 | LMNA (0.46) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5797814 | 0.93 | LMNA (0.41) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5797811 | 0.93 | LMNA (0.41) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5558888 | 0.90 | ELANE (0.44) | LMNAELANEALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5558886 | 0.90 | ELANE (0.44) | LMNAELANEALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5801025 | 0.90 | LMNA (0.39) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5801027 | 0.90 | LMNA (0.39) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5800716 | 0.88 | ALDH1A1 (0.36) | AKR1C3AKR1C2ALDH1A1KMT2A | |
| SCHEMBL5800719 | 0.88 | ALDH1A1 (0.36) | AKR1C3AKR1C2ALDH1A1KMT2A | |
| SCHEMBL5554437 | 0.88 | SRC (0.40) | LMNAELANEAKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |