Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800716 | 1.00 | ALDH1A1 (0.36) | ALDH1A1PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5813475 | 0.91 | PTGS2 (0.40) | PTGS2S1PR3 | |
| SCHEMBL5813479 | 0.91 | PTGS2 (0.40) | PTGS2S1PR3 | |
| SCHEMBL6425681 | 0.91 | PTGS2 (0.40) | PTGS2S1PR3 | |
| SCHEMBL5814349 | 0.91 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL5814350 | 0.91 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL5814808 | 0.90 | MGLL (0.34) | ALDH1A1PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5800622 | 0.90 | PTGS2 (0.36) | PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5800627 | 0.90 | PTGS2 (0.36) | PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5800816 | 0.89 | TSHR (0.40) | PTGS2AKR1C3AKR1C2MGLLPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |