Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.82 |
| ▸ | RAB9A | P51151 | 8/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.82 |
| ▸ | NPC1 | O15118 | 6/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.82 |
| ▸ | TSHR | P16473 | 3/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | PKM | P14618 | 2/20 | 0.82 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801394 | 0.91 | KDM4E (1.00) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL9413470 | 0.78 | KDM4E (0.74) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL29802287 | 0.75 | KDM4E (0.71) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL29824916 | 0.73 | NPC1 (0.68) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL22955317 | 0.73 | NPC1 (0.68) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL20740186 | 0.71 | KDM4E (1.00) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL19917859 | 0.70 | KDM4E (0.58) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL30436694 | 0.70 | RAB9A (0.64) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL14266173 | 0.70 | RAB9A (0.62) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL16329999 | 0.69 | KDM4E (0.56) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030127-A1 | COMPOSITION COMPRISING AT LEAST ONE SUBSTITUTED CARBOCYANINE DERIVATIVE, KERATIN FIBRE TREATMENT METHOD USING SAME, ASSOCIATED DEVICE AND USE THEREOF | L'OREAL (FR) | 2006-03-23 | — | — | WO | claimed |