Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797385 | 1.00 | POLB (0.45) | POLBALPLHSD17B10MAPK1FAAH | |
| SCHEMBL5808891 | 0.90 | HDAC6 (0.42) | POLBFAAHKDM4ENPC1RAB9A | |
| SCHEMBL5811982 | 0.89 | HDAC6 (0.55) | KDM4ENPC1RAB9AMITFXBP1 | |
| SCHEMBL5811979 | 0.89 | HDAC6 (0.55) | KDM4ENPC1RAB9AMITFXBP1 | |
| SCHEMBL5822676 | 0.88 | FAAH (0.41) | POLBALPLHSD17B10FAAHKDM4E | |
| SCHEMBL5799042 | 0.84 | FAAH (0.44) | ALPLHSD17B10FAAHKDM4ENPC1 | |
| SCHEMBL5795580 | 0.82 | HDAC6 (0.45) | ALPLHSD17B10FAAHKDM4ENPC1 | |
| SCHEMBL5799753 | 0.81 | HDAC6 (0.57) | POLBALPLHSD17B10FAAHKDM4E | |
| SCHEMBL5813364 | 0.80 | ALPL (0.46) | ALPLHSD17B10FAAHKDM4ENPC1 | |
| SCHEMBL5799615 | 0.80 | HDAC6 (0.43) | ALPLHSD17B10FAAHKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |