Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797106 | 0.91 | KDM4E (0.43) | FAAHKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5813566 | 0.91 | KDM4E (0.43) | FAAHKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5796465 | 0.89 | HDAC6 (0.52) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL5797381 | 0.84 | POLB (0.45) | FAAHALPLKDM4ERAB9ANPC1 | |
| SCHEMBL5797385 | 0.84 | POLB (0.45) | FAAHALPLKDM4ERAB9ANPC1 | |
| SCHEMBL5822676 | 0.82 | FAAH (0.41) | FAAHALPLKDM4ERAB9ANPC1 | |
| SCHEMBL5799071 | 0.80 | FAAH (0.42) | FAAHALPLKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5795580 | 0.80 | HDAC6 (0.45) | FAAHALPLKDM4ERAB9ANPC1 | |
| SCHEMBL5799753 | 0.79 | HDAC6 (0.57) | FAAHALPLKDM4ERAB9ANPC1 | |
| SCHEMBL5813364 | 0.78 | ALPL (0.46) | FAAHALPLKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |