Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 14/20 | 0.68 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.68 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.68 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.68 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518827 | 0.82 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL23002879 | 0.82 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL13966046 | 0.81 | — | — | |
| SCHEMBL497587 | 0.81 | GRIK1 (1.00) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL1476505 | 0.81 | GRIK1 (1.00) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL3508713 | 0.81 | — | — | |
| SCHEMBL3981383 | 0.81 | GRIK1 (1.00) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL3617857 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL638403 | 0.79 | GRIK1 (0.95) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Hydrochloric Acid SCHEMBL7214839 | 0.79 | GRIK1 (0.58) | GRIK1GRIK2GRM1GRM2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |