Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 12/20 | 0.95 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.95 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.95 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.95 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.54 |
| ▸ | TET3 | O43151 | 1/20 | 0.54 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981383 | 0.98 | GRIK1 (1.00) | GRIK1GRIK2GRM1GRM2TET2 | |
| SCHEMBL1476505 | 0.98 | GRIK1 (1.00) | GRIK1GRIK2GRM1GRM2TET2 | |
| SCHEMBL497587 | 0.98 | GRIK1 (1.00) | GRIK1GRIK2GRM1GRM2TET2 | |
| Hydrochloric Acid SCHEMBL4186334 | 0.95 | GRIK1 (0.95) | GRIK1GRIK2GRM1GRM2TET2 | |
| Hydrochloric Acid SCHEMBL6235798 | 0.95 | GRIK1 (0.95) | GRIK1GRIK2GRM1GRM2TET2 | |
| Lysine SCHEMBL7036667 | 0.81 | GRIK1 (0.69) | GRIK1GRIK2GRM1GRM2TET2 | |
| SCHEMBL1331820 | 0.81 | GRIK1 (0.71) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL1331822 | 0.81 | GRIK1 (0.71) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL5797481 | 0.79 | GRIK1 (0.68) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| Itaconate SCHEMBL27997562 | 0.79 | GRIK1 (0.67) | GRIK1GRIK2GRM1GRM2TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962800-B2 | Nucleic acids and proteins and methods for making and using them | BP CORPORATION NORTH AMERICA INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120266329-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | BP CORPORATION NORTH AMERICA INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-8119385-B2 | Nucleic acids and proteins and methods for making and using them | BP CORPORATION NORTH AMERICA INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110296543-A1 | NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-01 | — | — | US | disclosed |
| US-20100011456-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | VERENIUM CORPORATION (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120266329-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | POLN, POLM, POLI | GRIK1 4581/4885GRIK2 4590/4885GRM1 4287/4885 |
| US-20100011456-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | POLN, POLM, POLI | GRIK1 4581/4885GRIK2 4590/4885GRM1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.