Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554558 | 0.88 | AKR1C3 (0.47) | PPARGAKR1C3AKR1C2PPARA | |
| SCHEMBL5800618 | 0.84 | SRC (0.43) | ALOX5AKR1C3AKR1C2 | |
| SCHEMBL5553911 | 0.84 | ALDH1A1 (0.39) | AKR1C3AKR1C2 | |
| SCHEMBL5560384 | 0.83 | AKR1C2 (0.39) | TRPV1PPARGAKR1C3HRH3AKR1C2 | |
| SCHEMBL5554732 | 0.79 | PTGS2 (0.45) | PPARGAKR1C3AKR1C2PPARA | |
| SCHEMBL4377895 | 0.77 | AKR1C3 (0.57) | AKR1C3AKR1C2 | |
| SCHEMBL8354825 | 0.76 | AKR1C3 (0.51) | ALOX5PPARGAKR1C3AKR1C2 | |
| SCHEMBL5813860 | 0.75 | SCN9A (0.38) | TRPV1AKR1C3HRH3AKR1C2EPHX2 | |
| SCHEMBL3005490 | 0.73 | PTGS1 (0.71) | ALOX5PPARGAKR1C3AKR1C2PPARA | |
| SCHEMBL5554001 | 0.73 | PTGS1 (0.46) | ALOX5PPARGAKR1C3AKR1C2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |