Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797617 | 1.00 | CNR1 (0.38) | CNR1CNR2ELANEPTGS2SMN1; SMN2 | |
| SCHEMBL5801276 | 0.95 | PTGS2 (0.39) | CNR1CNR2ELANEPTGS2HPGD | |
| SCHEMBL5801273 | 0.95 | PTGS2 (0.39) | CNR1CNR2ELANEPTGS2HPGD | |
| SCHEMBL5798158 | 0.94 | ELANE (0.41) | CNR1CNR2ELANEPTGS2SMN1; SMN2 | |
| SCHEMBL5798014 | 0.91 | LMNA (0.41) | ELANEPTGS2SMN1; SMN2HPGDPOLB | |
| SCHEMBL5798016 | 0.91 | LMNA (0.41) | ELANEPTGS2SMN1; SMN2HPGDPOLB | |
| SCHEMBL5797205 | 0.89 | ELANE (0.38) | CNR1CNR2ELANEPTGS2SMN1; SMN2 | |
| SCHEMBL5797209 | 0.89 | ELANE (0.38) | CNR1CNR2ELANEPTGS2SMN1; SMN2 | |
| SCHEMBL5798896 | 0.89 | PTGS2 (0.45) | PTGS2 | |
| SCHEMBL5798899 | 0.89 | PTGS2 (0.45) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |