SCHEMBL5797759

SCHEMBL5797759

COC(=O)c1ccc(C=C(C)C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
AKR1C3 P42330 1/20 0.58
TSHR P16473 1/20 0.52
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
PTPN1 P18031 1/20 0.49
MAPT P10636 6/20 0.46
LMNA P02545 2/20 0.46
NPC1 O15118 2/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8184665 1.00 ALDH1A1 (0.59) ALDH1A1AKR1C3TSHRCA1CA2
SCHEMBL4803021 0.95 ALDH1A1 (0.54) ALDH1A1AKR1C3TSHRCA1CA2
SCHEMBL318840 0.84 ALDH1A1 (0.58) ALDH1A1TSHRCA1CA2TDP1
SCHEMBL318839 0.84 ALDH1A1 (0.58) ALDH1A1TSHRCA1CA2TDP1
SCHEMBL4661723 0.83 ALDH1A1 (0.66) ALDH1A1TSHRCA1CA2TDP1
SCHEMBL2462983 0.82 AKR1C3 (0.82) ALDH1A1AKR1C3TDP1L3MBTL1TP53
SCHEMBL2462984 0.82 AKR1C3 (0.82) ALDH1A1AKR1C3TDP1L3MBTL1TP53
SCHEMBL402110 0.81 ALDH1A1 (0.63) ALDH1A1TSHRCA1CA2TDP1
SCHEMBL7312808 0.81 AKR1C3 (0.53) ALDH1A1AKR1C3TSHRCA1CA2
SCHEMBL7312807 0.81 AKR1C3 (0.53) ALDH1A1AKR1C3TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0904043-B1 HIGH LATHER STYLING SHAMPOOS PROCTER & GAMBLE (US) 2000-02-02 EP claimed
US-9159356-B2 Non-resonant two-photon absorption recording material, non-resonant polymer two-photon absorption optical information recording medium, and recording/reproducing method FUJIFILM CORPORATION (JP) 2015-10-13 US disclosed
CN-101835735-A Bottom antireflective coating composition AZ ELECTRONIC MATERIALS USA 2010-09-15 CN disclosed
WO-2006025683-A1 ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2006-03-09 WO disclosed