Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DPYD | Q12882 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801051 | 0.74 | MEN1 (0.51) | ALDH1A1DPYDMAPTGAAATAD2 | |
| SCHEMBL4629034 | 0.69 | ALDH1A1 (0.53) | ALDH1A1DPYDMAPTGAAATAD2 | |
| SCHEMBL29872149 | 0.68 | MEN1 (0.57) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL21399551 | 0.68 | MEN1 (0.57) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL5800899 | 0.68 | DPYD (0.37) | ALDH1A1DPYDMAPTGAAATAD2 | |
| SCHEMBL5801006 | 0.68 | KMT2A (0.43) | ALDH1A1DPYDMAPTATAD2LMNA | |
| SCHEMBL5801042 | 0.68 | ALDH1A1 (0.41) | ALDH1A1DPYDKMT2AMEN1 | |
| SCHEMBL5800506 | 0.67 | CFTR (0.46) | ALDH1A1MAPTGAACYP19A1TSHR | |
| SCHEMBL11417188 | 0.66 | DPYD (0.46) | ALDH1A1DPYDMAPTGAAATAD2 | |
| SCHEMBL7668285 | 0.66 | DPYD (0.46) | ALDH1A1DPYDMAPTGAAATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |