Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801051 | 0.82 | MEN1 (0.51) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL11417188 | 0.71 | DPYD (0.46) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL5800506 | 0.71 | CFTR (0.46) | CYP19A1ALDH1A1GAAMAPTTSHR | |
| SCHEMBL29809206 | 0.69 | ALDH1A1 (0.67) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL11536497 | 0.69 | CYP19A1 (0.40) | CYP19A1DAO | |
| SCHEMBL16893950 | 0.69 | GAA (0.54) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL5797995 | 0.68 | ALDH1A1 (0.39) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL1918404 | 0.67 | ATAD2 (0.52) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL8537479 | 0.67 | MAPT (0.52) | DPYDCYP19A1ALDH1A1GAAATAD2 | |
| SCHEMBL7668285 | 0.67 | DPYD (0.46) | DPYDCYP19A1ALDH1A1GAAATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |