Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | DPYD | Q12882 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066662 | 0.75 | CA1 (0.63) | KMT2AALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL5801042 | 0.75 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1DPYDCA12 | |
| SCHEMBL5801051 | 0.75 | MEN1 (0.51) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL16652648 | 0.74 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL102177 | 0.72 | ATAD2 (0.52) | KMT2AALDH1A1LMNAMAPTATAD2 | |
| SCHEMBL24145206 | 0.71 | MAPT (0.62) | KMT2AALDH1A1MEN1MAPTNPSR1 | |
| SCHEMBL31511306 | 0.71 | MAPT (0.62) | KMT2AALDH1A1MEN1MAPTNPSR1 | |
| SCHEMBL38658521 | 0.71 | ATAD2 (0.47) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL5797950 | 0.70 | MEN1 (0.55) | KMT2AALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL1918404 | 0.68 | ATAD2 (0.52) | KMT2AALDH1A1LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |