Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 18/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905540 | 0.80 | OPRM1 (0.42) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL5798011 | 0.79 | DRD2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5194325 | 0.78 | DRD2 (0.48) | — | |
| SCHEMBL14291196 | 0.76 | SUV39H2 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL5247939 | 0.72 | GRM5 (0.47) | — | |
| SCHEMBL5905336 | 0.72 | MAPT (0.37) | OPRM1OPRL1OPRD1OPRK1SLC6A2 | |
| SCHEMBL5905435 | 0.71 | DRD2 (0.43) | — | |
| SCHEMBL5193321 | 0.71 | DRD2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5193723 | 0.71 | DRD2 (0.48) | — | |
| SCHEMBL5196095 | 0.71 | DRD2 (0.42) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006044174-A9 | ARYL SUBSTITUTED 8-AZABICYCLO[3.2.1]OCTANE COMPOUNDS AS LIGANDS OF THE MELANIN CONCENTRATING HORMONE RECEPTOR | NEUROGEN CORP (US) | 2006-07-20 | — | — | WO | claimed |