Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798053 | 0.89 | AKR1B1 (0.47) | P2RX7MEN1KMT2AMAPK1LMNA | |
| SCHEMBL31737601 | 0.78 | HDAC8 (0.48) | P2RX7MAPK1GAAHDAC8CYP3A4 | |
| SCHEMBL5798009 | 0.78 | P2RX7 (0.54) | P2RX7MAPK1LMNAHDAC8CYP1A2 | |
| SCHEMBL5797623 | 0.76 | LMNA (0.56) | P2RX7MEN1KMT2ALMNA | |
| SCHEMBL10061644 | 0.76 | P2RX7 (0.44) | P2RX7KMT2ALMNAHDAC8CYP3A4 | |
| SCHEMBL4926760 | 0.74 | MAPT (0.47) | P2RX7MEN1KMT2AMAPK1GAA | |
| SCHEMBL11733277 | 0.73 | P2RX7 (0.53) | P2RX7MAPK1HDAC8CYP1A2CYP3A4 | |
| SCHEMBL9097988 | 0.72 | P2RX7 (0.43) | P2RX7MAPK1HDAC8CYP3A4 | |
| SCHEMBL9097991 | 0.72 | KDM4E (0.47) | P2RX7MEN1KMT2AHDAC8CYP1A2 | |
| SCHEMBL20360782 | 0.72 | TAAR1 (0.43) | P2RX7MEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |