Sugi Predict

Sugi Predict / Compounds / SCHEMBL5797623

SCHEMBL5797623

SCHEMBL5797623

Cc1c(Cl)cccc1CNC(O)=S

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.56
▸ ALOX12 P18054 3/20 0.56
▸ HPGD P15428 1/20 0.56
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ P2RX7 Q99572 13/20 0.48
▸ MAPT P10636 1/20 0.46
▸ HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3126847 0.84 P2RX7 (0.56) LMNAALOX12HPGDP2RX7
SCHEMBL5798132 0.82 PNMT (0.48) LMNAALOX12HPGDMEN1KMT2A
SCHEMBL5795611 0.79 ALDH1A1 (0.47) LMNAALOX12HPGDMEN1KMT2A
SCHEMBL5794698 0.79 ALDH1A1 (0.50) LMNAALOX12HPGDMEN1KMT2A
SCHEMBL18255096 0.79 P2RX7 (0.54) LMNAALOX12HPGDP2RX7
SCHEMBL16709621 0.78 P2RX7 (0.53) LMNAALOX12HPGDP2RX7
SCHEMBL5797618 0.78 P2RX7 (0.53) LMNAALOX12HPGDP2RX7
SCHEMBL5798053 0.77 AKR1B1 (0.47) LMNAALOX12HPGDMEN1KMT2A
SCHEMBL18251704 0.77 ALDH1A1 (0.55) KMT2AP2RX7
SCHEMBL9711299 0.77 LMNA (0.45) LMNAALOX12HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006037468-A1 HIV REVERSE TRANSCRIPTASE INHIBITORS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) 2006-04-13 — — WO claimed