Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL11860029 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL5941322 | 1.00 | — | — | |
| Imidazole SCHEMBL27787391 | 0.97 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28109905 | 0.97 | — | — | |
| Imidazole SCHEMBL27607394 | 0.97 | — | — | |
| Imidazole SCHEMBL28744226 | 0.96 | ALDH1A1 (1.00) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL2684565 | 0.96 | ALDH1A1 (1.00) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL30382963 | 0.96 | — | — | |
| Imidazole SCHEMBL897 | 0.96 | — | — | |
| Imidazole SCHEMBL1331920 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981421-A | Cleaning composition capable of effectively removing scale and low in corrosivity and process | 河北电力长凯工贸有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-102432412-A | Preparation method of chiral sulfoxide proton pump inhibitor or pharmaceutically acceptable salt thereof | CHENGDU XINJIE HI TECH DEV CO LTD | 2012-05-02 | — | — | CN | disclosed |
| US-7115748-B2 | Method of making imidazole-2-thiones | ALLERGAN, INC. (US) | 2006-10-03 | — | — | US | disclosed |
| WO-2006062890-A1 | METHOD OF MAKING IMIDAZOLE-2-THIONES | ALLERGAN, INC. (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060122400-A1 | Method of making imidazole-2-thiones | ALLERGAN, INC. | 2006-06-08 | — | — | US | disclosed |
| CN-1171846-A | Hydrazide compounds useful as co-developers for black-and -white photothermographic elements | IMATION CORP (US) | 1998-01-28 | — | — | CN | disclosed |
| EP-0177808-A1 | 4-Methyl-5-thioformamidinomethylimidazole dihydrochloride | MECT CORPORATION (JP) | 1986-04-16 | — | — | EP | disclosed |
| EP-0177808-A1 | 4-Methyl-5-thioformamidinomethylimidazole dihydrochloride | MECT CORPORATION (JP) | 1986-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122400-A1 | Method of making imidazole-2-thiones | TST, INMT, TPMT | ALDH1A1 382/4885FKBP5 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.