Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553791 | 0.82 | KMT2A (0.41) | KMT2ACYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL5796829 | 0.76 | L3MBTL1 (0.52) | KMT2ACYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL14232073 | 0.76 | KMT2A (0.46) | KMT2AL3MBTL1BRD4BRD2BRD3 | |
| SCHEMBL5798118 | 0.75 | NOTUM (0.44) | KMT2ACYP2D6BRD4BRD2BRD3 | |
| SCHEMBL15196009 | 0.75 | KMT2A (0.41) | KMT2ACYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL14369799 | 0.70 | TMEM97 (0.39) | KMT2AALDH1A1KDM4EPKMTP53 | |
| SCHEMBL29809329 | 0.68 | ALDH1A1 (0.55) | KMT2ACYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL28803097 | 0.68 | ALDH1A1 (0.55) | KMT2ACYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL11792243 | 0.67 | P2RX4 (0.59) | KMT2ACYP1A2TSHRCYP2C19L3MBTL1 | |
| SCHEMBL2745392 | 0.67 | TYMP (0.45) | KMT2ACYP1A2CYP2C19ALDH1A1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |