Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918020 | 0.80 | L3MBTL1 (0.52) | L3MBTL1GSK3AGSK3BMAPK8MAPK9 | |
| SCHEMBL6449253 | 0.80 | L3MBTL1 (0.52) | L3MBTL1GSK3AGSK3BMAPK8MAPK9 | |
| SCHEMBL7822161 | 0.80 | L3MBTL1 (0.56) | L3MBTL1MAPK8MAPK9KMT2AMEN1 | |
| SCHEMBL5812520 | 0.80 | L3MBTL1 (0.52) | L3MBTL1GSK3AGSK3BMAPK8MAPK9 | |
| SCHEMBL5616888 | 0.78 | L3MBTL1 (0.50) | L3MBTL1CYP1A2CYP2D6CYP2C19GSK3A | |
| SCHEMBL9061909 | 0.76 | L3MBTL1 (0.52) | L3MBTL1TSHRGSK3AGSK3BMAPK8 | |
| SCHEMBL5798294 | 0.76 | KMT2A (0.44) | L3MBTL1CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL4358141 | 0.75 | L3MBTL1 (0.85) | L3MBTL1TSHRKMT2AMEN1MAPT | |
| SCHEMBL7837583 | 0.75 | ALDH1A1 (0.56) | L3MBTL1CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL29809329 | 0.75 | ALDH1A1 (0.55) | CYP1A2CYP2D6CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8325238-A | — | — | None | — | — | JP | disclosed |
| CN-111909100-B | Method for preparing uracil and thymine derivatives | 武汉大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-111909100-A | Method for efficiently preparing uracil and thymine derivatives | 武汉大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-102838549-A | New class of 1,5,6-substituted pyrimidine derivatives with anti-HIV virus effects | UNIV BEIJING | 2012-12-26 | — | — | CN | disclosed |
| CN-101016265-A | Preparation of HIV-1 reverse transcriptase inhibitor and application thereof | UNIV CAPITAL MEDICAL SCIENCES (CN) | 2007-08-15 | — | — | CN | disclosed |
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |
| JP-H08325238-A | 5-TRIFLUOROMETHYLURACIL DERIVATIVE AND ITS PRODUCTION | ASAHI GLASS CO LTD | 1996-12-10 | — | — | JP | disclosed |