Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712273 | 0.74 | LMNA (0.55) | TP53POLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL9453625 | 0.70 | KMT2A (0.54) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5800407 | 0.70 | KMT2A (0.44) | CES2CES1MAPTSMN1; SMN2LMNA | |
| Benzophenone SCHEMBL27490408 | 0.69 | POLB (0.79) | POLBMAPK1CES2CES1MAPT | |
| SCHEMBL9453651 | 0.69 | KMT2A (0.47) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27853418 | 0.68 | POLB (0.77) | POLBMAPK1CES2CES1MAPT | |
| SCHEMBL4473737 | 0.68 | P2RX4 (0.47) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL229627 | 0.68 | POLB (0.82) | POLBMAPK1CES2CES1MAPT | |
| Benzophenone SCHEMBL28231509 | 0.68 | POLB (0.82) | POLBMAPK1CES2CES1MAPT | |
| Bicarbonate SCHEMBL28199789 | 0.67 | POLB (0.70) | POLBMAPK1CES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |