Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798118 | 0.86 | NOTUM (0.44) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL5481632 | 0.79 | P2RX4 (0.52) | KMT2AMEN1ALDH1A1ARP2RX4 | |
| SCHEMBL9453625 | 0.78 | KMT2A (0.54) | KMT2AMEN1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL16880622 | 0.72 | P2RX4 (0.52) | KMT2AMEN1ALDH1A1KDM4EP2RX4 | |
| SCHEMBL5475973 | 0.71 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1KDM4EP2RX4 | |
| SCHEMBL7256423 | 0.70 | P2RX4 (0.39) | KMT2AMEN1ALDH1A1KDM4EP2RX4 | |
| SCHEMBL7260294 | 0.70 | P2RX4 (0.39) | KMT2AMEN1ALDH1A1P2RX4MAPT | |
| SCHEMBL5474617 | 0.70 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1P2RX4DBH | |
| SCHEMBL5798321 | 0.70 | TP53 (0.45) | KMT2AMEN1CES2CES1ALDH1A1 | |
| SCHEMBL5484208 | 0.69 | MAPT (0.45) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |