Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051108 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAHTTNPC1 | |
| Hydrochloric Acid SCHEMBL28366848 | 0.74 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAHTTNPC1 | |
| SCHEMBL4461351 | 0.73 | POLB (0.35) | POLBTRPA1ALDH1A1 | |
| SCHEMBL28941963 | 0.70 | ALDH1A1 (0.50) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL263784 | 0.69 | — | — | |
| SCHEMBL5019737 | 0.67 | POLB (0.48) | POLBTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1018454 | 0.66 | CYP3A4 (0.44) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL1018455 | 0.66 | CYP3A4 (0.44) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL7052300 | 0.66 | SLC1A2 (0.33) | ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL24568694 | 0.65 | EPHX1 (0.46) | POLBTRPA1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006055644-A2 | SYNTHESIS AND USE OF GLYCODENDRIMER REAGENTS | GENENCOR INTERNATIONAL, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006055437-A2 | SYNTHESIS AND USE OF GLYCODENDRIMER REAGENTS | GENENCOR INTERNATIONAL, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| US-20050272670-A1 | Synthesis and use of glycodendrimer reagents | DAVIS BENJAMIN G | 2005-12-08 | — | — | US | disclosed |
| US-6627744-B2 | A chemically modified mutant protein, e.g. an enzyme, having a substituted cysteine reacted with a glyosyslated thiosulfate; high esterase activity and low amidase activity of subtilisins; protease to degrade lectins | GENENCOR INTERNATIONAL, INC. | 2003-09-30 | — | — | US | disclosed |
| US-20020019039-A1 | Synthesis and use of glycodendrimer reagents | GENENCOR INTERNATIONAL, INC. | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019039-A1 | Synthesis and use of glycodendrimer reagents | STT3A, STT3B, PTMS | POLB 4838/4885TRPA1 3947/4885ALDH1A1 3111/4885 |
| US-20050272670-A1 | Synthesis and use of glycodendrimer reagents | STT3A, PTMS, STT3B | POLB 4841/4885TRPA1 3846/4885ALDH1A1 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.