Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.70 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.62 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095373 | 0.82 | PLOD2 (0.72) | PLOD2PLOD3PLOD1PTPN1MAPT | |
| SCHEMBL711849 | 0.82 | PLOD2 (1.00) | PLOD2PLOD3PLOD1PTPN1CA1 | |
| SCHEMBL584065 | 0.81 | PLOD2 (0.70) | PLOD2PLOD3PLOD1PTPN1GSK3B | |
| SCHEMBL313164 | 0.81 | PLOD2 (0.70) | PLOD2PLOD3PLOD1PTPN1PDPK1 | |
| SCHEMBL583455 | 0.81 | PLOD2 (0.70) | PLOD2PLOD3PLOD1PTPN1CA1 | |
| SCHEMBL1593867 | 0.81 | PLOD2 (0.70) | PLOD2PLOD3PLOD1PTPN1CA2 | |
| SCHEMBL523476 | 0.80 | PLOD2 (0.69) | PLOD2PLOD3PLOD1PTPN1GSK3B | |
| SCHEMBL14013115 | 0.79 | PLOD2 (0.68) | PLOD2PLOD3PLOD1PTPN1GSK3B | |
| SCHEMBL10613378 | 0.79 | PLOD2 (0.68) | PLOD2PLOD3PLOD1PTPN1CA2 | |
| SCHEMBL10613054 | 0.78 | PLOD2 (0.67) | PLOD2PLOD3PLOD1PTPN1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006036777-A2 | DIAGNOSIS OF DISEASES ASSOCIATED WITH COX-2 EXPRESSION | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2006-04-06 | — | — | WO | disclosed |
| US-20060067879-A1 | Diagnosis of diseases associated with COX-2 expression | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060067879-A1 | Diagnosis of diseases associated with COX-2 expression | PTGES2, PTGS2, PTGER2 | PLOD2 295/4885PLOD3 1562/4885PLOD1 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.