Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.70 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.62 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613378 | 0.98 | PLOD2 (0.68) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL11137727 | 0.95 | PLOD2 (0.64) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL22804725 | 0.84 | MAOB (0.61) | PLOD2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL711849 | 0.82 | PLOD2 (1.00) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL1095373 | 0.82 | PLOD2 (0.72) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL19919892 | 0.82 | NPC1 (0.65) | PLOD2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4588764 | 0.81 | PLOD2 (0.66) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL28718057 | 0.81 | PLOD2 (0.66) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL22805972 | 0.81 | PLOD2 (0.66) | PLOD2PLOD3PLOD1NPC1RAB9A | |
| SCHEMBL3247389 | 0.81 | PLOD2 (0.60) | PLOD2PLOD3PLOD1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917908-B1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYSTEM FOR PREPARATION OF CELECOXIB AND ANALOGS THEREOF | COUNCIL SCIENT IND RES (IN) | 2024-08-14 | — | — | EP | claimed |
| CN-118256718-A | Alpha-diketo lithium ion extractant and extraction system | 郑州天一萃取科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118256716-A | Gamma-diketo lithium ion extractant and extraction system | 郑州天一萃取科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118256717-A | Lithium ion extractant and extraction system | 郑州天一萃取科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| US-11802112-B2 | Continuous flow micro-total process system for preparation of celecoxib and analogs thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-10-31 | — | — | US | claimed |
| CN-115466277-A | Carboxyl functionalized time-resolved fluorescent microsphere and preparation method thereof | 苏州为度生物技术有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-114891030-A | Europium complex time-resolved fluorescent material and preparation method thereof | 苏州为度生物技术有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-113336779-B | Rare earth luminescent material, preparation method thereof and fluorescent sensing application | 中国计量大学 | 2022-06-28 | — | — | CN | claimed |
| US-20220127235-A1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYTEM FOR PREPARATION OF CELCOXIB AND ANALOGS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-04-28 | — | — | US | claimed |
| CN-109010837-B | Celecoxib composition with high solubility | 千辉药业（安徽）有限责任公司 | 2021-09-28 | — | — | CN | claimed |
| US-20070004924-A1 | such as (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-1-yl]benzenesulfonamide), celecoxib, via reacting 1,3-diketone and 4-sulfamidophenyl hydrazine halide salt in solvent system containing isopropanol | PHARMACIA CORPORATION | 2007-01-04 | — | — | US | claimed |
| EP-1507766-A4 | SYNTHESIS OF DIARYL PYRAZOLES | PHARMACIA CORP (US) | 2006-06-14 | — | — | EP | claimed |
| EP-1507766-A1 | SYNTHESIS OF DIARYL PYRAZOLES | Pharmacia Corporation (US) | 2005-02-23 | — | — | EP | claimed |
| US-20040024225-A1 | Synthesis of diaryl pyrazoles | PHARMACIA CORPORATION | 2004-02-05 | — | — | US | claimed |
| WO-2003099794-A1 | SYNTHESIS OF DIARYL PYRAZOLES | PHARMACIA CORPORATION (US) | 2003-12-04 | — | — | WO | claimed |
| EP-1167355-B1 | A crystalline form of celecoxib | FAKO ILACLARI A S (TR) | 2003-10-01 | — | — | EP | claimed |
| US-6391906-B2 | NON-STEROIDAL ANTI-INFLAMMATORY AGENTS | FAKO ILACLARI, S.A. (TR) | 2002-05-21 | — | — | US | claimed |
| US-20020016351-A1 | New crystals of celecoxib | ACTAVIS GROUP HF (IS) | 2002-02-07 | — | — | US | claimed |
| WO-2002000627-A1 | A CRYSTALLINE FORM OF CELECOXIB | FAKO ILACLARI A.S. (TR) | 2002-01-03 | — | — | WO | claimed |
| EP-1167355-A1 | A crystalline form of celecoxib | FAKO ILACLARI A.S. (TR) | 2002-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802112-B2 | Continuous flow micro-total process system for preparation of celecoxib and analogs thereof | PTGES2, PTGS2, CYP2J2 | PLOD2 3454/4885PLOD3 4085/4885PLOD1 4033/4885 |
| US-20020016351-A1 | New crystals of celecoxib | PTGS1, PTGER1, CYP2F1 | PLOD2 2957/4885PLOD3 3720/4885PLOD1 2266/4885 |
| US-20070004924-A1 | such as (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-1-yl]benzenesulfonamide), celecoxib, via reacting 1,3-diketone and 4-sulfamidophenyl hydrazine halide salt in solvent system containing isopropanol | KHK, GCK, SYMPK | PLOD2 3796/4885PLOD3 3171/4885PLOD1 3662/4885 |
| US-20040024225-A1 | Synthesis of diaryl pyrazoles | HDHD5, PDCD2L, HELZ | PLOD2 4000/4885PLOD3 4088/4885PLOD1 4417/4885 |
| US-20220127235-A1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYTEM FOR PREPARATION OF CELCOXIB AND ANALOGS THEREOF | PTGES2, PTGS2, P2RX2 | PLOD2 2433/4885PLOD3 3324/4885PLOD1 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.