Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206478 | 0.90 | RAB9A (0.57) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL14416710 | 0.83 | RAB9A (0.50) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3551022 | 0.82 | KMT2A (0.64) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL1512672 | 0.82 | KMT2A (0.63) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27902979 | 0.81 | KMT2A (0.61) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10907507 | 0.81 | LMNA (0.61) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL12890380 | 0.81 | SAE1 (0.57) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL16949648 | 0.81 | RAB9A (0.49) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL68678 | 0.80 | LMNA (0.59) | RAB9AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL12732390 | 0.80 | ALDH1A1 (0.79) | RAB9AKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5092916-A | — | — | None | — | — | JP | disclosed |
| WO-2006024885-A1 | PROCESS FOR THE PREPARATION OF POLYISOCYANATE/POLYSILICIC ACID BASED POLYADDITION AND HYBRID RESINS USING BLOCKED POLYISO-CYANATES AND BLOCKED POLYISOCYANATES USABLE IN THE PROCESS | POLINVENT FEJLESZTO, KIVITELEZO ÉS ÉRTÉKESÍTO KFT (HU) | 2006-03-09 | — | — | WO | disclosed |
| JP-H0592916-A | MEDICINE CAPABLE OF SUPPRESSING MELANOGENESIS FOR EXTERNAL USE | SANSHO SEIYAKU CO LTD | 1993-04-16 | — | — | JP | disclosed |