Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | GLI2 | P10070 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560788 | 0.93 | LMNA (0.34) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5560792 | 0.93 | LMNA (0.34) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5800286 | 0.92 | TRPV1 (0.36) | LMNACXCL8PTGS2ALDH1A1KDM4E | |
| SCHEMBL5559505 | 0.91 | AKR1C3 (0.36) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5559500 | 0.91 | AKR1C3 (0.36) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5558663 | 0.89 | AKR1C3 (0.37) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5558658 | 0.89 | AKR1C3 (0.37) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5558652 | 0.89 | AKR1C3 (0.37) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 | |
| SCHEMBL5798914 | 0.89 | PTGS2 (0.36) | AKR1C3AKR1C2CXCL8PTGS2MEN1 | |
| SCHEMBL5559451 | 0.88 | CYP3A4 (0.35) | LMNAAKR1C3AKR1C2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |