Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5561342 | 0.93 | TRPV1 (0.37) | TRPV1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5561347 | 0.93 | TRPV1 (0.37) | TRPV1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5799266 | 0.92 | LMNA (0.33) | CXCL8PTGS2MAPTMEN1KMT2A | |
| SCHEMBL5554482 | 0.91 | CCKBR (0.38) | TRPV1MEN1KMT2A | |
| SCHEMBL5554474 | 0.91 | CCKBR (0.38) | TRPV1MEN1KMT2A | |
| SCHEMBL5798914 | 0.90 | PTGS2 (0.36) | CXCL8PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL5800355 | 0.90 | PTGS2 (0.36) | TRPV1CXCL8PTGS2PTGS1MAPT | |
| SCHEMBL5560610 | 0.90 | TRPV1 (0.36) | TRPV1MEN1KMT2APOLB | |
| SCHEMBL5560614 | 0.90 | TRPV1 (0.36) | TRPV1MEN1KMT2APOLB | |
| SCHEMBL5560619 | 0.90 | TRPV1 (0.36) | TRPV1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |