Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.46 |
| ▸ | SCD | O00767 | 9/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799330 | 1.00 | RAB9A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5799066 | 0.94 | KMT2A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5809988 | 0.93 | SCD (0.46) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5809983 | 0.93 | SCD (0.46) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5799063 | 0.84 | RAB9A (0.48) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5810724 | 0.84 | MAPT (0.41) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5810719 | 0.84 | MAPT (0.41) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5807771 | 0.83 | GCGR (0.46) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5807764 | 0.83 | GCGR (0.46) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5823606 | 0.82 | PIN1 (0.40) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |