Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | SCD | O00767 | 11/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822231 | 0.94 | KMT2A (0.48) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5799236 | 0.92 | SCD (0.47) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5796348 | 0.89 | MEN1 (0.41) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5796715 | 0.88 | MAPT (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5799330 | 0.84 | RAB9A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5799332 | 0.84 | RAB9A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5799028 | 0.83 | MAPT (0.41) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5796946 | 0.83 | MTNR1A (0.43) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5799059 | 0.80 | NPC1 (0.39) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5798801 | 0.80 | HDAC1 (0.38) | MEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |