Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798606 | 0.82 | MAPK13 (0.46) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5809579 | 0.79 | MAPK11 (0.49) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5795738 | 0.79 | MAPK13 (0.46) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5795290 | 0.78 | MAPK13 (0.45) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5798480 | 0.73 | MAPK13 (0.40) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5796380 | 0.70 | MAPK11 (0.39) | MAPK13MAPK11CYP2C9MAPK12MAPK14 | |
| SCHEMBL5813023 | 0.69 | CYP2C9 (0.37) | MAPK13MAPK11CYP2C9MAPK12MAPK14 | |
| SCHEMBL5795724 | 0.69 | MAPK13 (0.37) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5799224 | 0.69 | MAPK13 (0.37) | MAPK13MAPK11CYP2C9FGFR1FGFR2 | |
| SCHEMBL5811310 | 0.69 | MAPK11 (0.53) | MAPK13MAPK11CYP2C9FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |