Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.51 |
| ▸ | MGLL | Q99685 | 10/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512607 | 0.81 | HSD11B1 (0.58) | HSD11B1MGLLFAAHTSHRHPGD | |
| SCHEMBL5777202 | 0.80 | HTR1A (0.50) | HTR1A | |
| SCHEMBL2653348 | 0.76 | HPGD (0.73) | HSD11B1HTR1AHPGD | |
| SCHEMBL2075037 | 0.76 | HPGD (0.68) | HSD11B1MGLLHTR1AHPGD | |
| SCHEMBL5634046 | 0.74 | HTR1A (0.49) | HSD11B1MGLLHTR1A | |
| SCHEMBL22406684 | 0.74 | HPGD (0.55) | HSD11B1MGLLHTR1AHPGD | |
| SCHEMBL19971712 | 0.74 | HTR1A (0.41) | HTR1A | |
| SCHEMBL5630460 | 0.72 | HPGD (0.54) | HSD11B1MGLLHTR1AHPGD | |
| Methane SCHEMBL7459255 | 0.72 | HTR1A (0.57) | HTR1A | |
| SCHEMBL19971721 | 0.71 | HTR1A (0.58) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358179-B1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PF MEDICAMENT (FR) | 2006-05-10 | — | — | EP | disclosed |
| EP-1358179-A1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PIERRE FABRE MEDICAMENT (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002064585-A1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PIERRE FABRE MEDICAMENT (FR) | 2002-08-22 | — | — | WO | disclosed |