Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL7454180 | 0.89 | HPGD (0.65) | HTR1AADRA1A | |
| SCHEMBL19971721 | 0.85 | HTR1A (0.58) | HTR1AADRA1A | |
| SCHEMBL6983237 | 0.84 | HTR1A (0.63) | HTR1AADRA1A | |
| SCHEMBL7466895 | 0.84 | HTR1A (0.57) | HTR1AADRA1A | |
| SCHEMBL6981877 | 0.83 | HTR1A (0.62) | HTR1AADRA1A | |
| SCHEMBL6985467 | 0.82 | HTR1A (0.55) | HTR1AADRA1A | |
| SCHEMBL2653348 | 0.82 | HPGD (0.73) | HTR1A | |
| SCHEMBL2075037 | 0.82 | HPGD (0.68) | HTR1A | |
| SCHEMBL19984097 | 0.82 | HTR1A (0.53) | HTR1AADRA1A | |
| SCHEMBL4021078 | 0.80 | HTR1A (0.53) | HTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119564-B1 | ARYL- 4-FLUORO-4- (2-PYRIDIN-2-YL-ETHYLAMINO)-METHYL]-PIPERIDIN-1-YL -METHANONE DERIVATIVES AS 5-HT1 RECEPTOR ANTAGONISTS | PF MEDICAMENT (FR) | 2002-12-18 | — | — | EP | disclosed |
| EP-1119564-A1 | ARYL- 4-FLUORO-4- (2-PYRIDIN-2-YL-ETHYLAMINO)-METHYL]-PIPERIDIN-1-YL -METHANONE DERIVATIVES AS 5-HT1 RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021953-A1 | ARYL-{4-FLUORO-4-[(2-PYRIDIN-2-YL-ETHYLAMINO)-METHYL]-PIPERIDIN-1-YL}-METHANONE DERIVATIVES AS 5-HT1 RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2000-04-20 | — | — | WO | disclosed |