Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249598 | 0.85 | KMT2A (0.65) | PARP10NR4A2MAOBMAOASMN1; SMN2 | |
| SCHEMBL6634107 | 0.84 | PARP10 (0.68) | PARP10NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL5843729 | 0.83 | LTA4H (0.63) | PARP10NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL1068959 | 0.82 | MAOB (0.70) | PARP10NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL4432728 | 0.82 | PARP10 (0.70) | PARP10NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL13719578 | 0.82 | NR4A1 (0.64) | PARP10NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL119689 | 0.82 | PARP10 (1.00) | PARP10NR4A1NR4A2NR4A3LMNA | |
| Diphenan SCHEMBL667724 | 0.81 | PLA2G10 (0.58) | PARP10LMNAL3MBTL1SRD5A2LTA4H | |
| SCHEMBL28694024 | 0.81 | PARP10 (0.64) | PARP10NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL1395785 | 0.81 | PARP10 (0.68) | PARP10NR4A1NR4A2NR4A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336704-B | Danshensu derivative and preparation method and medical application thereof | 上海大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-113336704-A | Danshensu derivative and preparation method and medical application thereof | 上海大学 | 2021-09-03 | — | — | CN | disclosed |
| WO-2006060082-A1 | TRICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS CHOLINESTERASE ACTIVITY INHIBITORS | THE GOVERNMENT OF THE U.S.A. as represented by THE SEC., DEPT. OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) | 2006-06-08 | — | — | WO | disclosed |