Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800253 | 1.00 | MAPT (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6852633 | 0.81 | ALDH1A1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6852642 | 0.81 | ALDH1A1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12132425 | 0.78 | ALDH1A1 (0.46) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9970465 | 0.77 | NPC1 (0.54) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9000568 | 0.76 | NPC1 (0.53) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9000576 | 0.76 | NPC1 (0.53) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6656717 | 0.76 | ALDH1A1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7106503 | 0.76 | ALDH1A1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL24817285 | 0.74 | ALDH1A1 (0.49) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006047167-A2 | 9 ALKYL AND 9 ALKYLIDENYL 6-0 ALKYL-11, 12 CARBAMATE KETOLIDE ANTIMICROBIALS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |