Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132427 | 0.88 | NPC1 (0.56) | ALDH1A1HTTMEN1KMT2ACASP1 | |
| SCHEMBL12132442 | 0.81 | CYP3A4 (0.42) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL13723845 | 0.81 | CHRNB2 (0.41) | KMT2ARAB9AOGACHRNB2CHRNA4 | |
| SCHEMBL6852642 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C19HTTMEN1 | |
| SCHEMBL6852633 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C19HTTMEN1 | |
| SCHEMBL5800255 | 0.78 | MAPT (0.47) | ALDH1A1CYP1A2CYP2C19HTTMEN1 | |
| SCHEMBL5800253 | 0.78 | MAPT (0.47) | ALDH1A1CYP1A2CYP2C19HTTMEN1 | |
| SCHEMBL13722897 | 0.77 | CHRNB2 (0.40) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL9970465 | 0.76 | NPC1 (0.54) | ALDH1A1CYP1A2CYP2C19HTTMEN1 | |
| SCHEMBL5620728 | 0.76 | HTT (0.60) | ALDH1A1CYP1A2CYP2C19HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063021-B2 | Ketolide anti-infective compounds | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-11-22 | — | — | US | disclosed |
| US-8063021-B2 | Ketolide anti-infective compounds | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-11-22 | — | — | US | disclosed |