Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579599 | 0.85 | CYP4F2 (0.50) | NAMPTLOXL2TBXAS1HPGDKDM4E | |
| SCHEMBL8580162 | 0.84 | PKM (0.43) | NAMPTPKMTBXAS1SMN1; SMN2HSD17B10 | |
| SCHEMBL21855464 | 0.81 | PKM (0.41) | NAMPTPKMTBXAS1SMN1; SMN2HSD17B10 | |
| SCHEMBL5894021 | 0.81 | AOC1 (0.47) | PKMTBXAS1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL3587236 | 0.81 | PKM (0.43) | PKMTBXAS1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL21855487 | 0.79 | CYP4F2 (0.50) | PKMTBXAS1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5893962 | 0.78 | MAPK1 (0.47) | PKMSMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL17377024 | 0.78 | MAPT (0.49) | PKMTBXAS1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL513027 | 0.77 | L3MBTL1 (0.60) | PKML3MBTL1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL31053374 | 0.77 | L3MBTL1 (0.60) | PKML3MBTL1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655296-A1 | Thrombin inhibitors | Graffinity Pharmaceuticals AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2006045459-A1 | THROMBIN INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2006-05-04 | — | — | WO | disclosed |